Endocrine Abstracts

Introduction: Bariatric surgery has important metabolic complications such as bone mass loss.Goal: To assess bone mineral density (BMD) after Roux-en-Y gastric by-pass (RYGB) in patients under standard calcium and vitamin D supplementation.Method: In patients with morbid obesity submitted to RYGB, we measured BMD with a dual X-ray densitometer. Using World Health Organization (WHO) criteria’s, values were compared with young c...

Introduction: Thyroid nodules are very common in the general population (20–75% ultrasound). There are clinical management criteria established by international societies and standardized cytological diagnostic criteria (Bethesda). However, there is still uncertainty in the management of category 3 (follicular lesion of undetermined significance). Objectives: To evaluate the clinical attitude to the cytological diagnosis of Bethesda category 3 (B3) in thyroid fine-needle ...

Objectives: Pregnant women who are overweight or obese have an increased risk of complications during pregnancy, as do pregnant women with type 1 diabetes mellitus (DM1). The objective of this study is to describe the prevalence of overweight/obesity in pregnant women with DM1, and associated complications.Patients and methods: Retrospective descriptive study of pregnant women with DM1 (2004–2014). Variables analyzed: age, initial body mass index (B...

Background: Acromegaly is the consequence of excessive growth hormone (GH) secretion, usually produced by a pituitary adenoma. In the last years, statins have been implicated in the response to treatment of patients with acromegaly. Although this fact is not very clear.Objective: To analyze whether pretreatment with statins modifies the adenoma molecular phenotype of the acromegalic patients and how this changes could help to influence the response to tr...

Objective: Obesity and overweight persist in patients with Cushing’s disease (CD) in remission, its persistence seems to be related to the duration of the disease. The aim of this study was to describe the persistence of overweight/obesity in patients with CD in remission and their relation to the duration of the disease.Patients and methods: Descriptive study of patients with CD (1995-2015). Variables analyzed: age, sex, body mass index (BMI), time...

Objective: Patients with Cushing’s disease (CD) may have adrenal nodules or hyperplasia related chronic hyperstimulation by adrenocorticotropic hormone (ACTH). The aim of this study was to describe the prevalence of adrenal nodules or hyperplasia in patients with CD and their relation with ACTH levels at diagnosis.Patients and methods: Descriptive study of patients with CD (1995–2015). Variables analyzed: age, sex, body mass in...

The clinical significance and potential morbidity of papillary thyroid microcarcinomas (PTMC) is discussed. Particularly the differences between those PTMC identified postoperatively in histological examination (incidentals), and those diagnosed preoperatively (non-incidentals). We retrospectively analysed differences in clinical presentation and course after treatment in these two groups. The study population consisted of 199 patients with PTMC who underwent surgery from 2000...

Introduction: Hypoparathyroidism (hypoPT) is the most frequent complication after thyroid surgery, usually as transient hypocalcaemia. Permanent parathyroid lesion is less frequent, but it can extend hospital stay and complicate postoperative management. Several preoperative factors predicting the development of hypoPT have been identified, including advanced age, hyperthyroidism, surgical experience and others. We evaluate the role of some potentially predictive factors in ou...

Objective: The aim of this study was to assess the utility of arterial calcium stimulation with hepatic venous sampling (ASVS) in the localization of tumors in patients with endogenous hyperinsulinism not detected with other methods.Patients and methods: We performed a retrospective study of 30 patients admitted to our hospital for hypoglycemia who underwent ASVS because the source of hyperinsulinism was not clearly identified by other imaging techniques...

Objetive: Evaluate the efficacy of subcutaneous HCG with or without FSH in male infertility associated to hypogonadotropic hypogonadism (HH).Patients and methods: Descriptive study of patients with HH treated with HCG s.c. with or without FSH, for fertility objective (2004–2011). The Treatment was initiated with HCG 500 UI/72 h s.c., periodic monitoring of testosterone and semen analysis was realized, adjusting doses up to 2500 UI/72 h. If no answer...